What Role do Systemic Antibiotics Play in the Treatment of Periodontal Disease?
Numerous Periodontists have evaluated the ADJUNCTIVE use of systemic antibiotics (by mouth) to halt the progression of gum (Periodontal) disease. Some benefit has been demonstrated when these medications are incorporated into the treatment protocol (used during such conservative procedures such as scaling and root planing).

Current data to suggest that the use of systemic adjunctive antibiotic therapy to reduce the need for periodontal surgery are limited and require further study for valication.

However, given the potential side effects of these drugs, including the development of resistent bacterial strains or increased growth of opportunistic organisms (yeast infections), incorporation of systemic antibiotic therapy into the routine management for the majority of adult periodontitis cases cannot be justified at this time.

Systemic antibiotic therapy should be reserved for patients with continuing periodontal breakdown despite meticulous scaling and root planing and oral hygiene care. In addition, patients at high risk for periodontal breakdown, such as juvenile periodontitis (genetic-predisposed) and patients with other early-onset forms of periodontitis, may be treated with antibiotcs in CONJUNCTION with conventional forms of treatment, as scaling and root planing.

Just What Antibiotics are Used in Treating Periodontal Disease:

    • Usual doseage: 500 Mg. taken twice per day for atleast 8 days
      • Dangerous side effect: Severe Diarhea or Collitis!
    • Usual doseage: 500 Mg. taken twice per day for atleast 8 days
  • METRONIDAZOLE(also known as FLAGYL)
    • Usual doseage: 500 Mg. taken twice per day for atleast 8 days
      • Dangerous side effects: Dizziness and Blurry Vision, along with Headache
  • CLINDAMYCIN- Usually used if a patient is allergic to "penicillin"
    • Usual doseage: 300 Mg. taken twice per day, but only for 5-6 days
    • Dangerous side effect: Severe Diarhea or Collitis!
    • Usual doseage: 500 Mg. taken twice per day for atleast 8 days
    • Usual doseage for Tetracycline: 500 Mg. taken four times per day for atleast 14 days
    • Usual doseage for Doxycline: 100 Mg. taken twice per day for atleast 14 days
    • Dangerous side effects:
      • Severe sunburn if exposure to bright sunshine
      • Severe stomach cramps and nausea
  • Combination of Antibiotics for Better Results:

    • How to take combination pills:
      • Usually you take TWO tablets of EACH per DAY or 4 Pills altogether:
        • Start off with Augmentin or Cipro before breakfast
        • Take Metronidazole before lunch
        • Take Augmentin (or Cipro) again before dinner
        • Lastly, take Metronidazole before bedtime

Please follow the instructions for taking antibiotics carefully. There can be very serious side effects that if not heeded can make you very sick. If you have any problems, discontinue them right away and call Dr. Mao.

One way to prevent diarhea is to take YOGURT ("live culture"-plain).


  • Usually, START the Morning of the FIRST VISIT for Scaling and Root Planing or Surgery


Richard Mao, D.M.D.
Practice Limited to Periodontics
E-Mailwith Questions:list your STATE


402 Severn Bldg.
8600 La Salle Rd.
Towson, Md. 21286
Tel:(410) 321-9595
707 N.Hickory Ave.
Bel Air, Md. 21014
Tel:(410) 879-6969