Professional Statement on
PerioChip chlorhexidine containing resorbable polymer
The PerioChip is
designed to be placed in a periodontal pocket > 5 mm after scaling and root
planing. This device releases chlorhexidine as the polymer is resorbed.
Published studies have indicated that subgingival administration of chlorhexidine in a
controlled release device reduces subgingival bacteria and improves gingival health.
Randomized controlled clinical trials that compared the efficacy of scaling and root
planing alone to scaling and root planing plus PerioChip revealed statistically
significant benefits of adjunctive chip use with regard to reducing probing depths (0.65
mm versus 0.95 mm) and gain of clinical attachment (0.58 mm versus 0.78 mm).
However, the magnitude of these changes was small (0.3 mm). Furthermore, it should be
noted that these are considered limited alterations in patients with advanced
periodontitis. Therefore, the magnitude of the results needs to be considered by each
practitioner in light of the defects being treated. Additional research needs to clarify
potential uses of this local delivery system.
At present, the Academy is aware of no data regarding the need for further surgical or
non-surgical treatment of sites after treatment with PerioChip. Furthermore, the Academy
is not aware of any studies that have addressed the use of PerioChip in diseases other
than adult periodontitis (i.e., localized juvenile periodontitis, rapid progressive
periodontitis). Similarly, the Academy is not aware of any investigations that have
addressed the utility of PerioChip in specific types of defects (i.e., furcations,
intrabony lesions). Long-term (>1 year) data of stability of treatment outcomes are
also not available.
Each practitioner must, of course, determine the usefulness of PerioChip in light of
the available data and the needs of the individual patient.